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KMID : 0383820110700050397
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Tuberculosis and Respiratory Diseases
2011 Volume.70 No. 5 p.397 ~ p.404
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Pandemic Influenza A/H1N1 Viral Pneumonia without Co-Infection in Korea: Chest CT Findings
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Son Jun-Seong
Kim Yee-Hyung
Lee Young-Kyung
Park So-Young
Choi Cheon-Woong
Park Myung-Jae
Yoo Jee-Hong
Kang Hong-Mo
Lee Jong-Hoo
Park Bo-Ram
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Abstract
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Background: To evaluate chest CT findings of pandemic influenza A/H1N1 pneumonia without co-infection.
Methods: Among 56 patients diagnosed with pandemic influenza A/H1N1 pneumonia, chest CT was obtained in
22 between October 2009 and Februrary 2010. Since two patients were co-infected with bacteria, the other twenty were evaluated. Predominant parenchymal patterns were categorized into consolidation, ground glass opacity (GGO), and mixed patterns. Distribution of parenchymal abnormalities was assessed.
Results: Median age was 46.5 years. The CURB-65 score, which is the scoring system for severity of community acquired pneumonia, had a median of 1. Median duration of symptoms was 3 days. All had abnormal chest x-ray findings. The median number of days after the hospital visit that Chest CT was performed was 1. The reasons for chest CT performance were radiographic findings unusual for pneumonia (n=13) and unexplained dyspnea (n=7). GGO was the most predominant pattern on CT (n=13, 65.0%). Parenchymal abnormalities were observed in both lungs in 13 cases and were more extensive in the lower lung zone than the upper. Central and peripheral distributions were identified in ten and nine cases, respectively. One showed diffuse distribution. Peribronchial wall thickening was found in 16 cases. Centrilobular branching nodules (n=7), interlobular septal thickening (n=4), atelectasis (n=1), pleural effusion (n=5), enlarged hilar and mediastinal lymph nodes (n=6 and n=7) were also noted.
Conclusion: Patchy and bilateral GGO along bronchi with predominant involvement of lower lungs are the most
common chest CT findings of pandemic influenza A/H1N1 pneumonia.
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KEYWORD
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Influenza A Virus, H1N1 Subtype, Tomography, X-Ray Computed, Pandemics, Pneumonia, Influenza Human
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